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Do Endorphins Help with Lymphoedema and Lipoedema?

  • Jeanine Mewburn
  • Aug 7, 2025
  • 2 min read

Endorphins—the “feel-good” hormones—can play a supportive role in managing lymphoedema and lipoedema by helping to reduce pain, elevate mood, and boost self-esteem.


These natural hormones are released by the body in response to physical activity, laughter, and even certain emotions. Endorphins act as natural painkillers by blocking pain signals and helping you function even during discomfort or stress. They also support appetite regulation and may aid in weight management. Low levels of endorphins have been associated with anxiety, depression, body aches, addiction, and sleep disturbances.


Two of the most effective ways to boost endorphin levels are physical activity and laughter:


A brisk walk can:

  • Elevate endorphin levels to improve mood, reduce stress, and promote a sense of well-being.

  • Increase serotonin, which helps regulate mood, appetite, and sleep, and reduce symptoms of anxiety and depression.

  • Release dopamine, a hormone associated with pleasure, motivation, and reward.


A good belly laugh can:

  • Trigger the release of endorphins and serotonin, contributing to mood improvement and pain relief.

  • Stimulate dopamine production, enhancing feelings of joy and satisfaction.


Laughter therapy is scientifically supported as a complementary approach for improving mental health.


While walking and laughing won’t cure lymphoedema or lipoedema, they can certainly be valuable additions to a broader management plan.


So walk more, laugh often.We don’t laugh because we’re happy—we’re happy because we laugh.


Watercolour inspired by a cartoon found on Pinterest (pinned by Bobbie McDonald) and shared on Facebook. Original artist unknown – happy to credit if identified.




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